Anti-p38 MAPK Monoclonal Antibody

品牌：solarbio | 货号：K000093M

英文名称 Anti-p38 MAPK Monoclonal Antibody
宿主 Mouse
别名 CSBP;CSBP1;CSBP2;CSPB1;EXIP;Mxi2;p38;p38ALPHA;PRKM14;PRKM15;RK;SAPK2A
应用 WB
稀释比例 WB 1:500.
交叉反应 Human Mouse Rat Monkey
蛋白分子量 40kDa
Gene ID 1432
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG1
免疫原 Purified recombinant human P38 MAPK Pprotein fragments expressed in E.coli.
性状 液体
Public Immunogen Range Purified recombinant human P38 MAPK Pprotein fragments expressed in E.coli.
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q16539
克隆号 5A1-C5-F11
克隆类型 Monoclonal Antibody
背景资料 The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

英文名称	Anti-p38 MAPK Monoclonal Antibody
宿主	Mouse
别名	CSBP;CSBP1;CSBP2;CSPB1;EXIP;Mxi2;p38;p38ALPHA;PRKM14;PRKM15;RK;SAPK2A
应用	WB
稀释比例	WB 1:500.
交叉反应	Human Mouse Rat Monkey
蛋白分子量	40kDa
Gene ID	1432
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG1
免疫原	Purified recombinant human P38 MAPK Pprotein fragments expressed in E.coli.
性状	液体
Public Immunogen Range	Purified recombinant human P38 MAPK Pprotein fragments expressed in E.coli.
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	Q16539
克隆号	5A1-C5-F11
克隆类型	Monoclonal Antibody
背景资料	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.