Anti-APP Polyclonal Antibody

品牌：solarbio | 货号：K001592P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001592P-50ul	solarbio	50ul	960.00元
K001592P-100ul	solarbio	100ul	1600.00元

英文名称 Anti-APP Polyclonal Antibody
别名 AAA;ABETA;ABPP;AD1;APPI;CTFgamma;CVAP;PN-II;PN2
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-200.
交叉反应 Human
蛋白分子量 87kDa
Gene ID 351
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human APP
性状 液体
Public Immunogen Range Recombinant protein of human APP
Subcellular Locations Membrane Single-pass type I membrane protein clathrin-coated pit
Swiss Prot P05067
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

英文名称	Anti-APP Polyclonal Antibody
别名	AAA;ABETA;ABPP;AD1;APPI;CTFgamma;CVAP;PN-II;PN2
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human
蛋白分子量	87kDa
Gene ID	351
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human APP
性状	液体
Public Immunogen Range	Recombinant protein of human APP
Subcellular Locations	Membrane Single-pass type I membrane protein clathrin-coated pit
Swiss Prot	P05067
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.