MCM7 Polyclonal Antibody
产品名称: MCM7 Polyclonal Antibody
英文名称: MCM7 Polyclonal Antibody
产品编号: K002218P
产品价格: null
产品产地: 北京市通州区马驹桥联
品牌商标: solarbio
更新时间: 2025-11-13T16:50:54
使用范围:
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市北京经济技术开发区环科中路16号26幢3层301
- 邮编 :
- 所在区域 : 北京
- 电话 : 181****6239 点击查看
- 传真 : 点击查看
- 邮箱 : 3193328036@qq.com
- 二维码 : 点击查看
Anti-MCM7 Polyclonal Antibody
品牌:solarbio | 货号:K002218P
| 英文名称 | Anti-MCM7 Polyclonal Antibody |
|---|---|
| 别名 | CDC47;MCM2;P1.1-MCM3;P1CDC47;P85MCM;PNAS146;PPP1R104 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 81kDa |
| Gene ID | 4176 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human MCM7 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human MCM7 |
| Subcellular Locations | Nucleus |
| Swiss Prot | P33993 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
