FITC标记的防御素α1/3抗体-抗体-抗体-生物在线
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FITC标记的防御素α1/3抗体

FITC标记的防御素α1/3抗体

商家询价

产品名称: FITC标记的防御素α1/3抗体

英文名称: Anti-DEFA1/alpha Defensin 1/FITC

产品编号: HZ-1697R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: IF=1:50-200

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 Rabbit Anti-DEFA1/alpha Defensin 1/FITC Conjugated antibody

FITC标记的防御素α1/3抗体

 

英文名称 Anti-DEFA1/alpha Defensin 1/FITC
中文名称 FITC标记的防御素α1/3抗体
别    名 Defensin, alpha 1; alpha Defensin 1/3; alpha Defensin 1+3; ; Defensin alpha 3; HNP1; HNP3; HP1; DEF1_HUMAN; Neutrophil defensin 1; HNP-1; HP-1; HP1; HP 1-56; Neutrophil defensin 1; Neutrophil defensin 2; HNP-2; HP-2; HP2; DEFA1; DEF1; DEFA2; MRS; DEF3_HUMAN; Neutrophil defensin 3; Defensin, alpha 3; HNP-3; HP-3; HP3; HP 3-56;   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 6.7kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human alpha Defensin 1/3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Defensins are a group of cyclic peptides containing 29-35 amino acids, which comprise approximately 30% of the total protein content of neutrophil azurophilic granules. Various functions have been reported for the defensins, including antibacterial and antifungal activity and chemotactic activity for monocytes.

Function:
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Subunit:
Dimer.

Subcellular Location:
Secreted.

Post-translational modifications:
ADP-ribosylation drastically reduces cytotoxic and antibacterial activities, and enhances IL8 production. 
Phosphorylation at Tyr-85 has been found in some cancer cell lines, and interferes with ADP-rybosylation.

Similarity:
Belongs to the alpha-defensin family.

Database links:

Entrez Gene: 1667 Human

Entrez Gene: 1668 Human

Entrez Gene: 728358 Human

Entrez Gene: 13216 Mouse

Omim: 125220 Human

SwissProt: P59665 Human

SwissProt: P59666 Human

SwissProt: P11477 Mouse

Unigene: 380781 Human

Unigene: 654448 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

防御素是一组含有29-35个氨基酸的环肽,约占嗜中性粒细胞天青颗粒总蛋白质含量的30%。据报道,防御素具有多种功能,包括抗菌和抗真菌活性以及对单核细胞的趋化活性。