APOE monoclonal antibody, clone 1H4
产品名称： APOE monoclonal antibody, clone 1H4
英文名称： APOE monoclonal antibody, clone 1H4
产品编号： MAB10490
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant APOE.
- Immunogen:
- Recombinant protein corresponding to human APOE.
- Host:
- Mouse
- Theoretical MW (kDa):
- 36
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis using APOE monoclonal antibody, clone 1H4 (Cat # MAB10490) against HEK293 (1) and ApoE (aa : 20-267)-hIgGFc transfected HEK293 (2) cell lysate.
- Entrez GeneID:
- 348
- Gene Name:
- APOE
- Gene Alias:
- AD2,LPG,MGC1571,apoprotein
- Gene Description:
- apolipoprotein E
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
- Other Designations:
- apolipoprotein E3
- Gene Pathway
- Related Disease
- Abortion, Habitual
- Achievement
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Adenoma
- AIDS Dementia Complex
- AIDS-Related Opportunistic Infections
- Akathisia, Drug-Induced
- Albuminuria
- Alcohol Amnestic Disorder
- Alcohol Withdrawal Seizures
- Alcoholism
- Alcohol-Related Disorders
- Alzheimer Disease
- Alzheimer disease
- Amnesia
- Amyloid Neuropathies, Familial
- Amyloidosis
- Amyotrophic Lateral Sclerosis