中心体相关蛋白激酶Nek2抗体
产品名称： 中心体相关蛋白激酶Nek2抗体
英文名称： NEK2
产品编号： bs-5732R
产品价格： null
产品产地： 北京
品牌商标： BIOSS
更新时间： 2025-12-02T14:04:13
使用范围： WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,
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Protein kinase that is involved in mitotic regulation. Integral component of the mitotic spindle-assembly checkpoint which is necessary for proper chromosome segregation during metaphase-anaphase transition. Required for association of MAD2L1 to kinetochore. Phosphorylates SGOL1. May have a role at the G2-M transition. May also play a role in meiosis. Isoform 1 but not isoform 2 appears to play a role in centrosome splitting. Isoform 1 phosphorylates and activates NEK11 in G1/S-arrested cells. Isoform 2, which is not present in the nucleolus, does not.