TMEM106B抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
TMEM106B抗体

TMEM106B抗体

商家询价

产品名称： TMEM106B抗体

英文名称： TMEM106BAntibody

产品编号： XY 20995-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 TMEM106B抗体Applications

Tested Applications: ELISA, WB, IHC, IF, IP
Cited applications WB
Specificity Reaction: Human, Mouse; Other species are not tested.Please decide the specificity by homology
Cited species Human
Positive WB detected in Mouse brain tissue, A549 cells, HeLa cells, human placenta tissue
Positive IP detected in Mouse brain tissue
Positive IHC detected in Human brain tissue
Positive IF detected in HeLa cells
Recommended dilution WB : 1:500-1:5000
IP : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:20-1:200
 TMEM106B抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev12NextView more validation data
  • 20995-1-AP;mouse brain tissuemouse brain tissue were subjected to SDS PAGE followed by western blot with 20995-1-AP(TMEM106B antibody) at dilution of 1:2000
  • 20995-1-AP;H-brainImmunohistochemical of paraffin-embedded human brain using 20995-1-AP(TMEM106B antibody) at dilution of 1:100 (under 10x lens)
  • 20995-1-AP;H-brainImmunohistochemical of paraffin-embedded human brain using 20995-1-AP(TMEM106B antibody) at dilution of 1:100 (under 40x lens)
  • 20995-1-AP;mouse brain tissueIP Result of anti-TMEM106B (IP:20995-1-AP, 3ug; Detection:20995-1-AP 1:1000) with mouse brain tissue lysate 6000ug.
  • 20995-1-AP;HeLa cellsImmunofluorescent analysis of HeLa cells using 20995-1-AP( TMEM106B Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Product Information TMEM106B抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: TMEM106B fusion protein ag14264 Full Name: Transmembrane protein 106B
Caculated Molecular
Weight:		 31 kDa Observed Molecular 
Weight:		 31-35kd
GenbankNo BC033901 GeneID: 54664
Symbol TMEM106B Synonyms FLJ11273, TMEM106B, transmembrane protein 106B
Background

TMEM106B is a genetic risk factor for frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP). Amyotrophic lateral sclerosis (ALS), like FTLD-TDP, is characterized by pathological TDP-43 inclusions. TMEM106B expression in the brain may be linked to mechanisms of disease in FTLD-TDP and risk alleles confer genetic susceptibility by increasing gene expression. TMEM106B can be showed as 31-40kDa and 60-75kDa (Glycosylated or Dimer) form in western blot test. TMEM106B抗体

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