Anti-MAPK14 Polyclonal Antibody

品牌：Solarbio | 货号：K001610P

K001610P-50ul	Solarbio	50ul	960.00元
K001610P-100ul	Solarbio	100ul	1600.00元

英文名称	Rabbit MAPK14 Polyclonal Antibody
应用2	WB IF
克隆类型2	Polyclonal Antibody
别名	CSBP;CSBP1;CSBP2;CSPB1;EXIP;Mxi2;PRKM14;PRKM15;RK;SAPK2A;p38;p38ALPHA
应用	WB,IF
稀释比例	WB1:500-1:2000 IF1:50-1:200
交叉反应	Human Mouse
蛋白分子量	41kDa
Gene ID	1432
保存	Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human MAPK14
性状	Lyophilized or Liquid
Swiss Prot	Q16539
克隆类型	Polyclonal Antibody
来源	Rabbit
背景资料	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.